期刊论文

Kou, Z.

中文

中南大学学报(医学版)

1672-7347

2018

43

1

41-48

10.11817/j.issn.1672-7347.2018.01.007

湖南省科技计划项目

本校为第一机构

目的:了解长期戒断甲基苯丙胺依赖患者的脑结构特点。方法:招募44名长期戒断甲基苯丙胺依赖患者(戒断时间大于14个月)及40名健康对照作为研究对象,在年龄、受教育程度、吸烟、饮酒方面进行匹配,使用西门子3.0T skyra头部正交线圈行结构功能磁共振研究;采用自制量表了解受试者基本情况和毒品使用情况,获取三维脑结构图像,然后采用基于体素的形态学分析法进行数据分析,行双样本t检验(cluster size>20,P

Objective: To explore the characteristics of brain structure in patients with long-term withdrawal of methamphetamine-dependence. Methods: A total of 44 patients with withdrawal of methamphetamine-dependent for more than 14 months were recruited, who met the diagnostic criteria for substance dependence in the fifth edition of the American Mental Disorders Diagnostic and Statistical Manual (DSM-V), and 40 healthy subjects were used as the control. In addition to the general scale of drug-relevant survey, the subjects received the 3.0T magnetic r...