Objective To find out the optimal matrix composition of Kechuanxuewei Patch.Methods Optimization of matrix composition has been determined.The optimum composition of the basic material was obtained by using orthogonal exprimental design.Results The optimum composition monostearin,stearic acid,Span-80,Tween-80,Lanolin,yellow vaseline,Extract is 1.5 ∶ 1.5 ∶ 1 ∶ 2 ∶ 1.5 ∶ 1.5:9.Conclusion The formation of the patch is good according to opti...