期刊论文

中文

中国现代药物应用

1673-9523

2012

6

15

5-6

10.14164/j.cnki.cn11-5581/r.2012.15.107

本校为第一机构

目的 以TiO2/Fe3+催化合成对硝基苯甲酸乙酯.方法 用TiO2/Fe3+催化合成对硝基苯甲酸乙酯.产品通过MS检测,并用正交试验确定了其最佳反应条件.结果 最佳反应条件为:酸醇摩尔比为1:6,反应温度为90℃,反应时间为2 h,收率达88%.结论 该法能顺利实现对硝基苯甲酸和乙醇的酯化.

Objective Ethyl 4-nitrobenzoate was synthesized catalyzed by TiO2/Fe3＋. Methods Eth- yl 4-nitrobenzoate was synthesized catalyzed by TiO2/Fe3＋ and tested by mass spectrum, the optimal conditions were confirmed by orthogonal tests. Results the optimal conditions were that the experiment yield is up to 88% when the temperature is 90℃, the reaction time is 2 hours, and the p-nitrohenzolc aeid：EtOH is 1：6. Conclusion TiO2/Fe3＋ can catal...