期刊论文

Peng, Q.-H.

中文

国际眼科杂志

1672-5123

2018

18

8

1359-1364

10.3980/j.issn.1672-5123.2018.8.01

Foundation items: National Natural Science Foundation of China (No.81574031); Hunan Provincial High Level Health Talent “225冶 Training Project; Project Supported by Hunan Provincial Science and Technology Department ( No. 2015SF2016-6); Project Supported by Hunan Provincial Development and Reform Commission (No. [2014] 658); Construction Project of Hunan Provincial Key Laboratory for Prevention and Treatment of Ophthalmology and Otolaryngology with Traditonal Chinese Medicine ( No. 2017TP1018); Changsha Science and Technology Project (No. KC1704005). Key Discipline of Ophthalmology of Chinese Medicine in Hunan University of Chinese Medicine, Changsha 410208 Hunan Province, China Correspondence to:Qing-Hua Peng and Han-Yu Tan. Key Discipline of Ophthalmology of Chinese Medicine in Hunan University of Chinese Medicine, Changsha 410208, Hunan Province, China. pqh410007@ 126. com; thy612@ 126. com Received: 2017-05-12摇 摇 Accepted: 2018-06-03

本校为第一机构

目的:观察不同浓度密蒙花滴眼液对去势雄兔泪腺细胞炎症因子TNF-α、IL-1β的影响,探讨不同浓度密蒙花滴眼液对去势雄兔干眼症模型的疗效.方法:将密蒙花原药材制备成低、中、高3种浓度滴眼液.将42只健康成年新西兰长耳白兔(雄性),随机分为A:空白组;B:模型组;C:低浓度密蒙花滴眼液组;D:中浓度密蒙花滴眼液组;E:高浓度密蒙花滴眼液组;F:安慰剂滴眼液组;G:睾酮组等7组,每组6只.除A组外其余6组实验用兔行双侧睾丸及附睾切除术.从术后第3天开始C、D、E、F组分别予相应滴眼液滴双眼.各组实验用兔,分别于术前和术后第4wk各进行一次Schirmer I试验(SIT)和泪膜破裂时间(BUT)测定.采用免疫组化法对泪腺细胞...

AIM:To observe the effect of different concentrations Buddleja offcinalis eye drops (BOED) to inflammatory factors of lacrimal gland cells of castrated male rabbit with dry eye. METHODS:Forty-two healthy adult New Zealand rabbits were randomly divided into 7 groups, 6 rabbits each group. Group A: blank group; Group B: model group; Group C: low concentrations BOED group; Group D: medium concentrations BOED; Group E: high concentrations BOED; Group F: the placebo group; Group G: testosterone groups. All rabbits of groups B to G were cut off bilat...