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The Potential Value of D-Dimer to Fibrinogen Ratio in Diagnosis of Acute Ischemic Stroke

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成果类型:
期刊论文
作者:
Chen, Xing;Li, Sijin;Chen, Wei;Xu, Fei;Wang, Yan;...
通讯作者:
Chen, X
作者机构:
[Chen, Wei; Ren, Biqiong; Li, Sijin; Chen, Xing; Zou, Guoying; Xu, Fei; Wang, Yan] Hunan Univ Chinese Med, Dept Lab Med, Clin Med Coll, Changsha 410208, Hunan, Peoples R China.
[Ren, Biqiong; Chen, X; Zou, Guoying; Xu, Fei] Second Peoples Hosp Hunan Prov, Clin Lab, 427 Furong Rd, Changsha 410007, Hunan, Peoples R China.
[Wang, Yan] Second Peoples Hosp Hunan Prov, Stroke Emergency, Changsha 410007, Hunan, Peoples R China.
通讯机构:
[Chen, X ] S
Second Peoples Hosp Hunan Prov, Clin Lab, 427 Furong Rd, Changsha 410007, Hunan, Peoples R China.
语种:
英文
关键词:
D dimer;fibrinogen;biological marker;fibrin degradation product;fibrin fragment D;fibrinogen;aged;analytical parameters;Article;brain infarction;brain ischemia;comorbidity;comparative study;computer assisted tomography;consciousness disorder;controlled study;d dimer fibrinogen ratio;diagnostic accuracy;diagnostic value;female;hospital patient;human;lacunar stroke;major clinical study;male;National Institutes of Health Stroke Scale;neuroimaging;nuclear magnetic resonance imaging;observational study;priority journal;blood;brain ischemia;case control study;cerebrovascular accident;differential diagnosis;middle aged;predictive value;reproducibility;very elderly;Aged;Aged, 80 and over;Biomarkers;Brain Ischemia;Case-Control Studies;Diagnosis, Differential;Female;Fibrin Fibrinogen Degradation Products;Fibrinogen;Humans;Male;Middle Aged;Predictive Value of Tests;Reproducibility of Results;Stroke
期刊:
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
ISSN:
1052-3057
年:
2020
卷:
29
期:
8
页码:
104918
机构署名:
本校为第一机构
院系归属:
临床医学院
摘要:
Introduction and Objective: At present, there is no hematology marker with high specificity to the diagnosis and differential diagnosis of acute ischemic stroke (AIS). How to use the existing test items to improve the diagnosis efficiency worthy of discussion. D-Dimer (DD) and fibrinogen (FIB) were the common indicators in thrombotic diseases, but D-dimer to fibrinogen ratio (D/F) in AIS has not been used in clinical practice. In this work, we focus on the evaluation of D/F. Methods: 90 AIS patients were selected as the observation group and 65...

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