Adcance in neurotrophin abnormality on pathogenesis of depression
作者：
王惠芹;王真真;林美妤;陈乃宏
作者机构：
[Un M.-Y.] Hunan Engineering Technology Center of Standardization and Function of Chinese Herbal Decoction Pieces, College of Pharmacy, Hunan University of Chinese Medicine, Changsha, 410208, China
[王真真] Neuroscience Center, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing, 100050, China
[王惠芹; 陈乃宏] Hunan Engineering Technology Center of Standardization and Function of Chinese Herbal Decoction Pieces, College of Pharmacy, Hunan University of Chinese Medicine, Changsha, 410208, China, Neuroscience Center, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing, 100050, China
Depression has been the“epidemic of the 21st century”,and its harm to the Chinese and even international citizens and society is becoming increasingly prominent.Neurotrophins are critical mediators to neuroplasticity,and the onset of depression is implicated in the abnormality of neurotrophins and their genes.The secretion of neurotrophins increases after antidepressant treatment,which promotes the survival of neurons and protects them from stress damage.Research on the association of brain-derived neurotrophic factor(BDNF),vascular endotheli...
