期刊论文

TangZhi-han;JiangZhi-sheng;Liu, LS

英文

Clinica Chimica Acta

0009-8981

2016

460

164-171

10.1016/j.cca.2016.06.044

This work was supported by the grants from the National Natural Science Foundation of China ( 81200217 , 81370376 ), the Natural Science Foundation of Hunan Province ( 2015JJ4097 ), the Key Project of Science and Technology Department of Hunan Province ( 2015JC3081 ), the Key Project of the Education Department of Hunan Province ( 15A137 ), the Visiting Scholar Foundation of Key Laboratory of Biorheological Science and Technology (Chongqing University), Ministry of Education ( CQKLBST-2014-002 , CQKLBST-2015-004 ), and by the Construct Program of the Key Discipline in Hunan Province ( [2011] 76 ).

本校为其他机构

MicroRNAs are a group of endogenously small non-coding RNA molecules that downregulate gene expression at the post-transcriptional level through binding to the 3'UTR of target mRNAs. Recent findings have revealed a key role for microRNAs in the pathophysiological processes of atherosclerosis. As a complex disease, atherosclerosis is influenced by a combination of multiple genes and environmental factors. Both of them play a role in atherogenesis by affecting different types of cells (such as endothelial cell, vascular smooth muscle cell and monocyte/macrophage) function. MicroRNAs control the ...