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Causal relationship between hormone levels and lung cancer: a Mendelian randomization study

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成果类型:
期刊论文
作者:
Feng, Zhiying;Fu, Jingmin;Wang, Kangyu;Yang, Jiaxin;Jiang, Xuelian;...
通讯作者:
Wu, Q
作者机构:
[Jiang, Xuelian; Feng, Zhiying; Yang, Jiaxin; Fu, Jingmin; Wang, Kangyu] Hunan Univ Chinese Med, Dept Tradit Chinese Med, Coll Tradit Chinese Med, Changsha, Hunan, Peoples R China.
[Wu, Qiong] Hunan Univ Chinese Med, Coll Humanities & Management, Dept Humanities & Management, Changsha, Hunan, Peoples R China.
通讯机构:
[Wu, Q ] H
Hunan Univ Chinese Med, Coll Humanities & Management, Dept Humanities & Management, Changsha, Hunan, Peoples R China.
语种:
英文
关键词:
Mendelian randomization;hormone levels;lung adenocarcinoma;lung cancer;lung squamous cell carcinoma;small cell carcinoma
期刊:
FRONTIERS IN ENDOCRINOLOGY
ISSN:
1664-2392
年:
2025
卷:
16
页码:
1462531
基金类别:
The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by Excellent Youth Project of Hunan Provincial Department of Education (23B0371).
机构署名:
本校为第一且通讯机构
院系归属:
中医学院
摘要:
BACKGROUND: Lung cancer is a highly prevalent neoplastic disease in various regions of the world, but the mechanism of its occurrence, development, and metastasis is not clear. Different hormone levels have different potential roles in the occurrence, development, and metastasis of lung cancer, but the association between hormone levels and lung cancer is not clear. OBJECTIVE: This study aims to explore the causal relationship between hormone levels and lung cancer using Mendelian randomization. Sensitivity and heterogeneity tests were conducted to ensure the reliability of the results, offeri...

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