[Wang, Dong-Xin; Li, Xiao-Song] Hunan Prov Brain Hosp, Res Inst Mental & Sanitat, 427,Sect 3 Furong Middle Rd, Changsha 410007, Hunan, Peoples R China.

[Yang, Ying; Huang, Xiao-Song; Li, Xiao-Hui; Tang, Jia-Yu] Hunan Prov Brain Hosp, Med Dept Neurol, Changsha 410007, Hunan, Peoples R China.

[Zhang, Xi] Hunan Tradit Chinese Med Univ, Clin Med Sch, Changsha 410006, Hunan, Peoples R China.

[Zhou, Bin; Huang, Hong-Xing; Liu, Bo; Liu, Kun; Zou, Shu-Cheng] Hunan Prov Brain Hosp, Dept Neurosurg, Changsha 410007, Hunan, Peoples R China.

[Xiao, Hui-Qiong] Hunan Prov Brain Hosp, Dept Sci Res, Changsha 410007, Hunan, Peoples R China.

[Li, XS ; Wang, XY ] H

Hunan Prov Brain Hosp, Res Inst Mental & Sanitat, 427,Sect 3 Furong Middle Rd, Changsha 410007, Hunan, Peoples R China.

Hunan Prov Brain Hosp, Inst Clin Trials Drugs, 427,Sect 3 Furong Middle Rd, Changsha 410007, Hunan, Peoples R China.

1 methyl 4 phenylpyridinium;1,2,3,6 tetrahydro 1 methyl 4 phenylpyridine;adenovirus E1B protein;lactate dehydrogenase;microRNA;microRNA 96;parkin;pramipexole;protein bcl 2;protein BNip3;unclassified drug;antiparkinson agent;BNip3 protein, mouse;membrane protein;microRNA;Mirn96 microRNA, mouse;mitochondrial protein;pramipexole;animal experiment;animal model;animal tissue;apoptosis;Article;behavior assessment;cell viability;controlled study;enzyme release;gene overexpression;gene targeting;human;human cell;immunofluorescence;male;mitophagy;mouse;MPP+-induced neurotoxicity;nerve injury;neuroprotection;nonhuman;Parkinson disease;priority journal;protein targeting;real time reverse transcription polymerase chain reaction;TUNEL assay;Western blotting;animal;C57BL mouse;dose response;drug effect;metabolism;mitophagy;nerve cell;parkinsonism;physiology;tumor cell line;Animals;Antiparkinson Agents;Cell Line, Tumor;Dose-Response Relationship, Drug;Humans;Male;Membrane Proteins;Mice;Mice, Inbred C57BL;MicroRNAs;Mitochondrial Proteins;Mitophagy;Neurons;Parkinsonian Disorders;Pramipexole