Objective: To explore the effects of Compound Qinbo Decoction (CQD) on the intestinal mucosa of ulcerative colitis (UC) through the Notch signaling pathway.Methods: The UC rat model, established using 2,4,6- Trinitrobenzene sulfonic acid (TNBS)/ethanol, was divided into the UC group, mesalazine (MS) group and CQD group. Normal rats were set as the normal group (n = 10). The pathological changes, messager RNA (mRNA) levels and protein expressions of Notch 1 and hairy and enhancer of split 1 (Hes1), epithelial cell proliferation in colon tissues were detected. Primary rat colon epithelial NCM460...
