Abnormal resting-state cerebral-limbic functional connectivity in bipolar depression and unipolar depression

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成果类型：

期刊论文

作者：

Liu, Chang;Pu, Weidan*;Wu, Guowei;Zhao, Jie;Xue, Zhimin

通讯作者：

Pu, Weidan

作者机构：

[Zhao, Jie; Liu, Chang] Brains Hosp Hunan Prov, Dept Psychiat, Changsha, Hunan, Peoples R China.

[Liu, Chang] Hunan Univ Tradit Chinese Med, Postdoctoral Res Mobile Stn, Changsha, Hunan, Peoples R China.

[Wu, Guowei; Xue, Zhimin] Cent S Univ, Mental Hlth Inst, Xiangya Hosp 2, Changsha, Hunan, Peoples R China.

[Wu, Guowei; Xue, Zhimin] Cent S Univ, State Key Lab Med Genet, Changsha, Hunan, Peoples R China.

[Pu, Weidan] Cent S Univ, Xiangya Hosp 2, Med Psychol Ctr, Changsha, Hunan, Peoples R China.

通讯机构：

[Pu, Weidan] C

Cent S Univ, Xiangya Hosp 2, Med Psychol Ctr, Changsha, Hunan, Peoples R China.

语种：

英文

关键词：

Depression;Cerebral-limbic;Functional activity;Resting-state

期刊：

BMC Neuroscience

ISSN：

1471-2202

年：

2019

卷：

期：

页码：

1-8

DOI：

10.1186/s12868-019-0508-6

基金类别：

This research was supported by Provincial technology innovation guide program funded by the Hunan Department of Science and Technology (2017SK50312 to Dr. C Liu), a grant of the National Natural Science Foundation of China (81171287 to Dr. ZM Xue). The design of the study, collection and analysis were supported by the National Natural Science Foundation of China (81171287), the interpretation of data and writing the manuscript was provided by a grant of the Provincial technology innovation guide program, funded by the Hunan Department of Science and Technology (2017SK50312).

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摘要：

Background: Distinctive patterns of functional connectivity (FC) abnormalities in neural circuitry has been reported in patients with bipolar depression (BD) and unipolar depression (UD). However, it is unclear that whether this distinct functional connectivity patterns are diagnosis specific between BD and UD. This study aimed to compare patterns of functional connectivity among BD, UD and healthy controls (HC) and determine the distinct functional connectivity patterns which can differentiate BD from UD. Method: Totally 23 BD, 22 UD, and 24 H...

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Abnormal resting-state cerebral-limbic functional connectivity in bipolar depression and unipolar depression

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