期刊论文

Influence of Jiawei Danxuan Koukang on oral submucosal fibrosis and the level of autophagy in rats

中文

中国医药导报

1673-7210

2023

20

24

9-15

10.20047/j.issn1673-7210.2023.24.02

81874496:国家自然科学基金 20C1389:湖南省教育厅科学研究一般项目 S202110541057:湖南省级大学生创新创业训练计划项目

本校为第一机构

目的探讨加味丹玄口康对大鼠口腔黏膜下纤维化(OSF)及其自噬水平的影响。方法选取SPF级SD雄性大鼠24只(180~200 g,4~8周龄),采用随机数字表法将其分为空白组、模型组和加味丹玄口康组,每组8只。模型组和加味...展开更多 目的探讨加味丹玄口康对大鼠口腔黏膜下纤维化(OSF)及其自噬水平的影响。方法选取SPF级SD雄性大鼠24只(180~200 g,4~8周龄),采用随机数字表法将其分为空白组、模型组和加味丹玄口康组,每组8只。模型组和加味丹玄口康组在大鼠双侧颊黏膜组织注射槟榔碱0.2 ml(10 mg/ml),1次/2 d,同时每天使用小牙刷沾取适量槟榔碱均匀施力刷大鼠双侧颊黏膜,持续8周,观察到大鼠颊黏膜出现白色病变...

Objective To investigate the influence of Jiawei Danxuan Koukang on oral submucous fibrosis(OSF)and the level of autophagy in rats.Methods Twenty-four SPF male SD rats(180-200 g,4-8 weeks old)were randomly divided into blank group,model group,and Jiawei Danxuan Koukang ...MORE Objective To investigate the influence of Jiawei Danxuan Koukang on oral submucous fibrosis(OSF)and the level of autophagy in rats.Methods Twenty-four SPF male SD rats(180-200 g,4-8 weeks old)were randomly divided into blank group,model group,and Jiawei Danxuan Koukang gr...