The author(s) declare that financial support was received for the research and/or publication of this article. This study was supported by the Natural Science Foundation of Hunan Province of China (2023JJ60292, 2023JJ30339 and 2025JJ90073), the Major Scientific Research Project of National Clinical Key Specialty (Z2023096), the Major Scientific Research Project for High-level Talents in Health of Hunan Province (R2023071), the Key Research and Development Plan of Hunan Province (2022SK2163 and 2022SK2124), the Clinical Medical Research Center Fund of Hunan Province (2021SK4022 and 2023SK4020), the project of Hunan Provincial Administration of Traditional Chinese Medicine (A2024041), Hunan University of Traditional Medicine Institutional Project (2024XYLH194) and Hunan University of Traditional Chinese Medicine graduate student innovation project (2024CX071 and 2024CX143).