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Diterpenoids from the Feces of Trogopterus xanthipes

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成果类型:
期刊论文
作者:
Zhao, Jun;Zhu, Hua-Jie;Zhou, Xiao-Jiang;Yang, Tong-Hua;Wang, Yuan-Yuan;...
通讯作者:
Li, Yan
作者机构:
[Wang, Yuan-Yuan; Li, Yan; Zhao, Jun; Zhu, Hua-Jie; Cheng, Yong-Xian; Su, Jia] Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China.
[Zhao, Jun] Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China.
[Zhou, Xiao-Jiang] Hunan Univ Tradit Chinese Med, Coll Pharm, Changsha 410007, Hunan, Peoples R China.
[Yang, Tong-Hua] First Peoples Hosp Yunnan Prov, Dept Hematol, Kunming 650032, Peoples R China.
通讯机构:
[Li, Yan] C
Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China.
语种:
英文
关键词:
Animals;Antineoplastic Agents;Phytogenic/ch [Chemistry];Phytogenic/ip [Isolation & Purification];Phytogenic/pd [Pharmacology];China;Diterpenes/ch [Chemistry];Diterpenes/ip [Isolation & Purification];Diterpenes/pd [Pharmacology];Drug Screening Assays;Antitumor;Feces/ch [Chemistry];Humans;Inhibitory Concentration 50;Sciuridae/me [Metabolism]
期刊:
JOURNAL OF NATURAL PRODUCTS
ISSN:
0163-3864
年:
2010
卷:
73
期:
5
页码:
865-869
基金类别:
Chinese Academy of SciencesChinese Academy of Sciences [2007PY01-48]; Sino-German International Collaboration [2009ACO11]; Ministry of Science and Technology of ChinaMinistry of Science and Technology, China [2008ZX09401-004]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [30770235, 30873141]
机构署名:
本校为其他机构
院系归属:
药学院
摘要:
Three new isopimarane diterpenoids, trogopteroids A-C (1-3), four new aromatic diterpenoids, trogopteroids D-G (4-7), and 12 known diterpenoids were isolated from the feces of Trogopterus xanthipes. Their structures were identified using spectroscopic methods. The relative configuration of 1 was confirmed by quantum calculations. Compound 1 represents the first example of a norisopimarane diterpenoid with an 8alpha,15alpha-olide ring. With the exception of compound 14, all diterpenoids were eval...

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