期刊论文

Leukopenia and thrombocytopenia caused by amisulpride

中文

药物不良反应杂志

1008-5734

2017

19

2

130-131

10.3760/cma.j.issn.1008-5734.2017.02.011

本校为第一机构

1例32岁女性患者因精神分裂症给予氨磺必利0.8 g口服,2次/d,用药前血常规检查结果正常。服药第26天,患者WBC降至2.3 ×10~9/L,中性粒细胞计数(NEUT)1.4 ×10~9/L,加用鲨肝醇片100 mg、利可君片20 mg,3次/d。服药第32天,患者WBC 3.7 × 10~9/L,NEUT 2.2 × 10~9/L,PLT 65×10~9/L,给予重组人白细胞介素11注射液1.5 mg/d皮下注射,连续7 d。7 d后复查,患者WBC 3.9 × 10~9/L,NEUT 2.5 × 10~9/L,PLT 113 ×10~9/L。因治疗需要患者仍继续服用氨磺必利。用药第51天,患者偶发倦怠乏力、头昏头痛,WBC 2.7 × 10~9/L,NEUT 1.4 × 10~9/L。遂将氨磺必利逐渐减量并停用,改为口服奥氮平20 mg/d。停用氨磺必...

A 32-year-old female patient with schizophrenia received amisulpride 0.8g twice daily. The results of her routine blood test were normal before taking medicine. On day 26 of administration,the results of routine blood test showed white blood cell count (WBC) 2.3×10~9/L, neutrophil count (NEUT) 1.4 × 10~9/L. She was given batilol tablet 100 mg and leucogen tablet 20 mg three times daily. On day 32 of administration, the results of routine blood test showed WBC 3.7 × 10~9/L,NEUT 2.2 × 10~9/L, platelet count (PLT) 65 × 10~9/L. The patient rec...