It is well known that microRNAs (miRNAs) play pivotal roles in gene expression, transcriptional regulation and other important biological processes. An impressive body of literature indicates that miRNAs and mRNAs work cooperatively to form an important part of gene regulatory modules which are extensively involved in cancer. However, with the accumulation of available data, it is a great challenge to identify cancer related miRNA regulatory modules and uncover their precise regulatory mechanism. This paper proposed a novel computational framework by combining gene expression and interaction d...
