Parthenolide Inhibits Angiogenesis in Esophageal Squamous Cell Carcinoma Through Suppression of VEGF

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Tian, Bo;Xiao, Yuhang;Ma, Junliang;Ou, Wei;Wang, Hui;...

通讯作者：

Su, Min;Wang, Wenxiang

作者机构：

[Yang, Desong; Li, Xu; Wang, Wenxiang; Tang, Jinming; Wu, Zhining; Zhou, Yong; Ma, Junliang; Wu, Jie; Zhang, Baihua; Tian, Bo; Su, Min] Cent South Univ, Hunan Canc Hosp, Dept Thorac Surg 2, Changsha, Peoples R China.

[Yang, Desong; Su, Min; Wang, WX; Li, Xu; Wang, Hui; Wang, Wenxiang; Tang, Jinming; Wu, Zhining; Zhou, Yong; Ma, Junliang; Wu, Jie; Zhang, Baihua; Tian, Bo] Cent South Univ, Affiliated Canc Hosp, Xiangya Sch Med, Changsha, Peoples R China.

[Su, Min; Wang, WX; Wang, Hui; Wang, Wenxiang; Ma, Junliang; Tian, Bo] Cent South Univ, Hunan Key Lab Translat Radiat Oncol, Hunan Canc Hosp, Changsha, Peoples R China.

[Xiao, Yuhang] Cent South Univ, Xiangya Hosp, Dept Pharm, Xiangya Sch Med, Changsha, Peoples R China.

[Ou, Wei] First Peoples Hosp Yue Yang, Dept Pharm, Yueyang, Peoples R China.

通讯机构：

[Su, M; Wang, WX] C

Cent South Univ, Affiliated Canc Hosp, Xiangya Sch Med, Changsha, Peoples R China.

Cent South Univ, Hunan Key Lab Translat Radiat Oncol, Hunan Canc Hosp, Changsha, Peoples R China.

语种：

英文

关键词：

parthenolide;esophageal squamous cell carcinoma;NF-кB;VEGF;AP-1

期刊：

OncoTargets and Therapy

ISSN：

1178-6930

年：

2020

卷：

页码：

7447-7458

DOI：

10.2147/OTT.S256291

基金类别：

Health and Family Planning Commission of Hunan Province [B20180545, C2019074]; Natural Science Foundation of Hunan ProvinceNatural Science Foundation of Hunan Province [2017JJ2173, 2019JJ50968, 2019JJ50358]; Fundamental Research Funds for the Central Universities of Central South University [502211903]

机构署名：

本校为其他机构

院系归属：

第二中医临床医学院

药学院

摘要：

Background: Parthenolide (PT), the effective active ingredient of the medicinal plant, feverfew (Tanacetum parthenium), has been used as an anti-inflammatory drug due to its involvement in the inhibition of the NF-kappa B pathway. Moreover, recent studies have demonstrated the anti-tumor effect of PT in several cancers. However, the effect of PT on esophageal carcinoma remains unclear to date. In this study, we examined the inhibitory effects of PT and its underlying mechanism of action in human esophageal squamous cell carcinoma (ESCC) cells - Eca109 and KYSE-510. Methods: The proliferation a...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Parthenolide Inhibits Angiogenesis in Esophageal Squamous Cell Carcinoma Through Suppression of VEGF

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问