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Wall shear stress and its role in atherosclerosis

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成果类型:
期刊论文
作者:
Zhou, Manli;Yu, Yunfeng;Chen, Ruiyi;Liu, Xingci;Hu, Yilei;...
作者机构:
[Yu, Yunfeng; Hu, Yilei; Zhou, Manli; Liu, Xingci; Ma, Zhiyan; Jian, Weixiong; Gao, Lingwei] Hunan Univ Chinese Med, Coll Tradit Chinese Med, Changsha, Peoples R China.
[Yu, Yunfeng; Liu, Xingci; Chen, Ruiyi] Hunan Univ Chinese Med, Affiliated Hosp 1, Changsha, Peoples R China.
[Jian, Weixiong] Hunan Univ Chinese Med, Hunan Prov Key Lab, Natl Key Discipline Tradit Chinese Med Diagnost, Changsha, Peoples R China.
[Wang, Liping] Hunan Univ Med, Coll Rehabil Med & Hlth Care, Huaihua, Peoples R China.
语种:
英文
关键词:
wall shear stress;atherosclerosis;endothelial cells;haemodynamic factors;biological factors;CFD
期刊:
Frontiers in Cardiovascular Medicine
ISSN:
2297-055X
年:
2023
卷:
10
页码:
499
基金类别:
National Natural Science Foundation of China [81973753]; Natural Science Foundation of Hunan Province [2022JJ30433]
机构署名:
本校为第一机构
院系归属:
中医学院
第一中医临床学院
摘要:
Atherosclerosis (AS) is the major form of cardiovascular disease and the leading cause of morbidity and mortality in countries around the world. Atherosclerosis combines the interactions of systemic risk factors, haemodynamic factors, and biological factors, in which biomechanical and biochemical cues strongly regulate the process of atherosclerosis. The development of atherosclerosis is directly related to hemodynamic disorders and is the most important parameter in the biomechanics of atherosclerosis. The complex blood flow in arteries forms rich WSS vectorial features, including the newly p...

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