Objective To study the effect of harvest time on the quality of Evodia rutaecarpa, to provide reference for the rational use of medicine Evoclia rutaecarpa. Methods HPLC was used to detect the content of evodine, evodiamine and rutaecarpine in Evodia rutaecarpa. The content of 3 chemicals was based on the quality of Evodia rutaecarpa derived from different harvest period. Results The content of the 3 chemical compounds increased firstly and then kept stable and reduced lastly in different haverst time. Conclusion The best harvest time was at th...