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Role of CALCR expression in liver cancer: Implications for the immunotherapy response

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成果类型:
期刊论文
作者:
Wang, Sijia;Wang, Wei;Zeng, Jia
通讯作者:
Zeng, J
作者机构:
[Wang, Sijia; Zeng, Jia] Hunan Univ Chinese Med, Dept Hlth Management, Hosp 1, 95 Shaoshan Middle Rd, Changsha 410001, Hunan, Peoples R China.
[Wang, Wei] Hunan Univ Tradit Chinese Med, Grad Sch, Changsha 410001, Hunan, Peoples R China.
通讯机构:
[Zeng, J ] H
Hunan Univ Chinese Med, Dept Hlth Management, Hosp 1, 95 Shaoshan Middle Rd, Changsha 410001, Hunan, Peoples R China.
语种:
英文
关键词:
calcitonin receptor;ferroptosis;fibrosis;genomic heterogeneity;liver hepatocellular carcinoma
期刊:
MOLECULAR MEDICINE REPORTS
ISSN:
1791-2997
年:
2025
卷:
31
期:
2
机构署名:
本校为第一且通讯机构
院系归属:
第一中医临床学院
研究生院
摘要:
Liver hepatocellular carcinoma (LIHC) is a prevalent and lethal malignancy with a complex molecular landscape. Fibrosis and ferroptosis are implicated in LIHC progression, yet their roles remain to be elucidated. The present study investigated the expression and prognostic significance of calcitonin receptor (CALCR), a gene that intersects the pathways of fibrosis and ferroptosis, across LIHC and other types of cancer. Data were obtained from The Cancer Genome Atlas and the Molecular Signatures Database. LIHC patients were classified into two c...

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