An fMRI-based neural marker for migraine without aura

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成果类型：

期刊论文

作者：

Tu, Yiheng;Zeng, Fang;Lan, Lei;Li, Zhengjie;Maleki, Nasim;...

通讯作者：

Kong, J;Liang, FR

作者机构：

[Kong, Jian; Tu, Yiheng; Maleki, Nasim; Lang, Courtney; Park, Joel] Massachusetts Gen Hosp, Dept Psychiat, Charlestown, MA 02129 USA.

[Kong, Jian; Tu, Yiheng; Maleki, Nasim; Lang, Courtney; Park, Joel] Harvard Med Sch, Charlestown, MA 02129 USA.

[Zeng, Fang; Lan, Lei; Liang, Fanrong; Li, Zhengjie] Chengdu Univ Tradit Chinese Med, Teaching Hosp 3, Chengdu, Sichuan, Peoples R China.

[Chen, Jun; Liu, Bo] Guangdong Prov Hosp Chinese Med, Dept Radiol, Guangzhou, Peoples R China.

[Wang, Chenchen] Tufts Med Ctr, Ctr Complementary & Integrat Med, Div Rheumatol, Boston, MA 02111 USA.

通讯机构：

[Kong, J ] M

[Liang, FR ] C

Massachusetts Gen Hosp, Dept Psychiat, Charlestown, MA 02129 USA.

Harvard Med Sch, Charlestown, MA 02129 USA.

Chengdu Univ Tradit Chinese Med, Teaching Hosp 3, Chengdu, Sichuan, Peoples R China.

语种：

英文

期刊：

NEUROLOGY

ISSN：

0028-3878

年：

2020

卷：

期：

页码：

E741-E751

DOI：

10.1212/WNL.0000000000008962

基金类别：

NIH/National Center for Complementary and Integrative Health [R01 AT008563, R33 AT009310, R33AT009341, R34DA046635, R21AT008707]; [81871443]

机构署名：

本校为其他机构

院系归属：

针灸推拿与康复学院

摘要：

OBJECTIVE: To identify and validate an fMRI-based neural marker for migraine without aura (MwoA) and to examine its association with treatment response. METHODS: We conducted cross-sectional studies with resting-state fMRI data from 230 participants and machine learning analyses. In studies 1 through 3, we identified, cross-validated, independently validated, and cross-sectionally validated an fMRI-based neural marker for MwoA. In study 4, we assessed the relationship between the neural marker and treatment responses in migraineurs who received a 4-week real or sham acupuncture treatment, or w...

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An fMRI-based neural marker for migraine without aura

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