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MicroRNA-146a and miR-99a are potential biomarkers for disease activity and clinical efficacy assessment in psoriasis patients treated with traditional Chinese medicine

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成果类型:
期刊论文
作者:
Yang, Zhibo;Zeng, Bijun*;Tang, Xueyong;Wang, Haizhen;Wang, Chang;...
通讯作者:
Zeng, Bijun
作者机构:
[Huang, Pan; Zeng, Bijun; Wang, Chang; Tang, Xueyong; Wang, Haizhen; Yang, Zhibo; Pan, Yi] Hunan Univ Chinese Med, Affiliated Hosp 2, Dept Dermatol, 233 Caie North Rd, Changsha 410005, Hunan, Peoples R China.
[Yan, Zhangren] Tradit Chinese Hosp Jiangxi Prov, Dept Dermatol, 445 Bayi Rd, Nanchang 330019, Jiangxi, Peoples R China.
[Xu, Bin] Wuhan 1 Hosp, Dept Dermatol, 215 Zhongshan Rd, Wuhan 430022, Hubei Province, Peoples R China.
通讯机构:
[Zeng, Bijun] H
Hunan Univ Chinese Med, Affiliated Hosp 2, Dept Dermatol, 233 Caie North Rd, Changsha 410005, Hunan, Peoples R China.
语种:
英文
关键词:
Psoriasis;Microarray;Traditional Chinese medicine (TCM);Zhuhuang Granule (ZG);PBMCs
期刊:
Journal of Ethnopharmacology
ISSN:
0378-8741
年:
2016
卷:
194
页码:
727-732
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81273769]
机构署名:
本校为第一且通讯机构
院系归属:
第二中医临床医学院
摘要:
Ethnopharmacological relevance Psoriasis is a common chronic inflammatory skin disease. A number of clinical investigations have indicated that traditional Chinese medicine (TCM) is an effective and safe treatment for psoriasis. Zhuhuang Granule (ZG) is a modified formulation of Zhuhuang Decoction, which is used traditionally in China for the treatment of psoriasis in clinical practice. Aim of the study Recent studies have found that microRNAs (miRNAs) play important roles in the pathogenesis of some skin diseases. The objective of our study wa...

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