"Drug Synthesis"involves a wide range of content and develops dramatically.In the era of big data great challenge existing in the teaching process,it is necessary to perform teaching reformation.To construct the reasonable course content containing the foundation and the frontier knowledge system is the basis of teaching reformation,the application of teaching skills with interest as the forerunner is the students'learning motivation,the use of the modern education teaching methods combined with subject itself is the key way to help students learning,and the improvement of students'professiona...