The therapeutic effect and mechanism of Chinese medicine Xuan-Yun-Ding on posterior circulation ischemia with vertigo in a rabbit model

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成果类型：

期刊论文

作者：

Liu Chunhua;Li Zhixiong;Wu Dahua;Yuan Chunyun;Deng Haoqin;...

作者机构：

[Liu Chunhua] Hunan Univ Chinese Med, Coll Integrated Tradit Chinese & Western Med, Changsha, Hunan, Peoples R China.

[Li Zhixiong] Hunan Univ Chinese Med, Med Sch, Changsha, Hunan, Peoples R China.

[Wu Dahua] Hunan Univ Chinese Med, Affiliated Hosp Integrated Tradit Chinese & Weste, Dept Encephalopathy, Changsha, Hunan, Peoples R China.

[Yuan Chunyun; Yuan Sisi] Hunan Univ Chinese Med, Affiliated Hosp Integrated Tradit Chinese & Weste, Dept Geriatr, Changsha, Hunan, Peoples R China.

[Deng Haoqin] Chinese Peoples Liberat Army, Hosp 458, Dept Tradit Chinese Med, Guangzhou, Guangdong, Peoples R China.

语种：

英文

关键词：

Posterior circulation ischemia;vertigo;Xuan-Yun-Ding;puerarin;Chinese medicine

期刊：

PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES

ISSN：

1011-601X

年：

2021

卷：

期：

页码：

843-854

DOI：

10.36721/PJPS.2021.34.3.REG.843-854.1

基金类别：

Hunan Province natural fund [12JJ3090]; Project of scientific research of traditional Chinese medicine in Hunan [2012146]

机构署名：

本校为其他机构

院系归属：

医学院

中西医结合学院

摘要：

The aim of research is to unveil the mechanisms of the beneficial effects of XYD on PCIV in a rabbit model. 40 New Zealand white rabbits were randomly divided into 5 groups,including normal control group (NC), model control group (MC), low-dose of XYD group (LXYD), high-dose of XYD group (HXYD) and Yang-Xue-Qin-Nao group (YXQN). PCIV rabbit model was established by feeding high-fat diet companied with paravertebral sclerotherapy and rotation exercise. The general observation, step-down test, rheoencephalogram, blood tests, histopathological detection and the plasma concentration of the effecti...

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The therapeutic effect and mechanism of Chinese medicine Xuan-Yun-Ding on posterior circulation ischemia with vertigo in a rabbit model

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