The regulatory role and clinical application prospects of circRNA in the occurrence and development of CNS tumors

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Zhang, Bo;Zhang, Hao;Wang, Zeyu;Cao, Hui;Zhang, Nan;...

通讯作者：

Cheng, Quan;Peng, RJ

作者机构：

[Peng, Renjun; Zhang, Hao; Zhang, Xun; Cheng, Quan; Liang, Xisong; Zhang, Bo; Wang, Zeyu; Zhang, Liyang; Dai, Ziyu; Wen, Jie] Cent South Univ, Xiangya Hosp, Dept Neurosurg, Changsha, Peoples R China.

[Peng, Renjun; Zhang, Xun; Cheng, Quan; Liang, Xisong; Zhang, Bo; Zhang, Liyang; Dai, Ziyu; Wen, Jie] Cent South Univ, Xiangya Hosp, Natl Clin Res Ctr Geriatr Disorders, Changsha, Peoples R China.

[Zhang, Hao] Chongqing Med Univ, Affiliated Hosp 2, Dept Neurosurg, Chongqing, Peoples R China.

[Wang, Zeyu] Univ Edinburgh, Inst Regenerat & Repair, MRC Ctr Regenerat Med, Edinburgh EH16 4UU, Scotland.

[Cao, Hui] Hunan Univ Chinese Med, Sch Clin Med, Dept Psychiat, Changsha, Peoples R China.

通讯机构：

[Peng, RJ ; Cheng, Q] C

Cent South Univ, Xiangya Hosp, Dept Neurosurg, Changsha 410008, Hunan, Peoples R China.

语种：

英文

关键词：

circRNA;CNS tumors;chemotherapy;immunotherapy;radiotherapy

期刊：

CNS Neuroscience & Therapeutics

ISSN：

1755-5930

年：

2024

卷：

期：

页码：

e14500-

DOI：

10.1111/cns.14500

基金类别：

National Natural Science Foundation of China [82073893, 81703622, 81901268]; Natural Science Foundation of Hunan Province [2022JJ20095]; Hunan Provincial Health Committee Foundation of China [202204044869]

机构署名：

本校为其他机构

院系归属：

临床医学院

摘要：

The precise risk factors and molecular mechanisms underlying CNS tumors remain unverified. Growing evidence suggests that Circular RNAs (circRNAs) have numerous significant biological functions in disease progression. In this review, we provide an overview of the relationship between circRNAs and CNS tumors and discuss the diagnostic and therapeutic potential of circRNAs in CNS tumors. Abstract Background Central nervous system (CNS) tumors originate from the spinal cord or brain. The study showed that even with aggressive treatment, malignant ...

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The regulatory role and clinical application prospects of circRNA in the occurrence and development of CNS tumors

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