Objective To explore the effect of biofeedback therapy on depression among undergraduates.Methods 32 students with the diagnostic criteria for depression received the biofeedback therapy for 30 minutes twice a week,6 weeks in total.The effect was as-sessed by self-rating depressive scale (SDS) and Symptom Checklist 90(SCL-90).Results The scale scores of the depression factor of SDS and SCL-90 were lower significantly than those before biofeedback therapy.The difference between pretest and posttest had sta-tistical significance (t=7.17,9.12;P