期刊论文

Lin, G.-Q.

中文

中南大学学报(医学版)

1672-7347

2005

30

4

399-402

10.3321/j.issn:1672-7347.2005.04.006

湖南省自然科学基金项目（02jjy2053）；

本校为其他机构

目的:检测冠心病患者血浆血管性血友病因子(von Willebrand factor, vWF)及可溶性E-选择素(soluble E-selectin, sE-selectin)的变化,探讨其在冠心病发病机制、病情诊治及监测中的意义.方法:用酶联免疫的方法(ELISA法)测定60例冠心病患者血浆vWF及sE-选择素的水平,并选取20例体检者作为对照;通过病史询问及调查获取实验组冠心病危险因素的资料,进一步分析其与冠心病的关系.结果:冠心病组的血浆vWF及sE-选择素水平明显高于对照组(P=0.017及P

OBJECTIVE: To observe the changes of plasma von Willebrand factor (vWF) and soluble E-selectin (sE-selectin) in patients with coronary artery disease (CAD) and evaluate their clinic significance. METHODS: The level of plasma vWF and sE-selectin of 60 cases with coronary artery disease were detected by enzyme-linked immunosorbent assay (ELISA) and 20 healthy persons acted as the control group. Risk factors for coronary artery disease were obtained by asking the medical history and the relation ship was analyzed with coronary artery disease. RESULTS: The plasma vWF and sE-selectin levels of CAD ...