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The role of lncRNA-mediated pyroptosis in cardiovascular diseases

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成果类型:
期刊论文
作者:
Hu, Bo;Chen, Wen;Zhong, Yancheng*;Tuo, Qinhui
通讯作者:
Zhong, Yancheng;Tuo, Q
作者机构:
[Zhong, Yancheng; Tuo, Qinhui; Chen, Wen; Zhong, YC; Hu, Bo] Hunan Univ Chinese Med, Med Sch, Hunan Key Lab Vasc Biol & Translat Med, Changsha, Peoples R China.
通讯机构:
[Tuo, Q ; Zhong, YC] H
Hunan Univ Chinese Med, Med Sch, Hunan Key Lab Vasc Biol & Translat Med, Changsha, Peoples R China.
语种:
英文
关键词:
Cardiovascular disease (CVD);LncRNA - long noncoding RNA;gasdermins (GSDMs);pyroptosis;Inflammatory
期刊:
Frontiers in Cardiovascular Medicine
ISSN:
2297-055X
年:
2023
卷:
10
基金类别:
Key Research and Development Projects of Hunan Provincial Science and Technology Department [2022SK2011, 2023TP1018]; Science and Technology Innovation Program of Hunan Province [2021RC4064]; Scientific Research Fund of Hunan Provincial Education Department [22B0361]
机构署名:
本校为第一且通讯机构
院系归属:
医学院
摘要:
Cardiovascular disease (CVD) is the leading cause of death worldwide. Pyroptosis is a unique kind of programmed cell death that varies from apoptosis and necrosis morphologically, mechanistically, and pathophysiologically. Long non-coding RNAs (LncRNAs) are thought to be promising biomarkers and therapeutic targets for the diagnosis and treatment of a variety of diseases, including cardiovascular disease. Recent research has demonstrated that lncRNA-mediated pyroptosis has significance in CVD and that pyroptosis-related lncRNAs may be potential targets for the prevention and treatment of speci...

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