Prognostic Value of Immunotyping Combined with Targeted Therapy in Patients with Non-Small-Cell Lung Cancer and Establishment of Nomogram Model

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Tian, Sha;Guo, Yinmei;Fu, Jiajun;Li, Zijing;Li, Jing;...

通讯作者：

Tian, X.

作者机构：

[Tian, Xuefei; Tian, Sha] Hunan Univ Chinese Med, Coll Integrated Chinese & Western Med, Dept Internal Med, Changsha, Peoples R China.

[Guo, Yinmei] Hunan Univ Chinese Med, Hunan Key Lab Tradit Chinese Med Prescript & Synd, Changsha, Peoples R China.

[Fu, Jiajun] Med Sch Hunan Univ Chinese Med, Changsha, Peoples R China.

[Li, Zijing] Hunan Univ Chinese Med, Acupuncture Moxibust Tuina & Rehabil, Changsha, Peoples R China.

[Li, Jing] First Hosp Hunan Univ Chinese Med, Dept Oncol, Changsha, Peoples R China.

通讯机构：

Department Of Internal Medicine, College Of Integrated Chinese And Western Medicine, Hunan University Of Chinese Medicine, China

语种：

英文

期刊：

Computational and Mathematical Methods in Medicine

ISSN：

1748-6718

年：

2022

卷：

2022

DOI：

10.1155/2022/3049619

基金类别：

Hunan Province "Domestic First-Class Cultivation Discipline" Integrated Traditional Chinese and Western Medicine Open Fund Project [2019ZXJH02]; Chinese Medicine Scientific Research Program of Hunan Province [2021235]; Changsha Municipal Natural Science Foundation [kq2014087]; Excellent Youth Program of Hunan Provincial Education Department [21B0384]

机构署名：

本校为第一机构

院系归属：

医学院

中西医结合学院

摘要：

Objective. Bioinformatics methods were used to analyze non-small-cell lung cancer gene chip data, screen differentially expressed genes (DEGs), explore biomarkers related to NSCLC prognosis, provide new targets for the treatment of NSCLC, and build immunotyping and line-map model. Methods. NSCLC-related gene chip data were downloaded from the GEO database, and the common DEGs of the two datasets were screened by using the GEO2R tool and FunRich 3.1.3 software. DAVID database was used for GO analysis and KEGG analysis of DEGs, and protein-protein interaction (PPI) network was constructed by STR...

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Prognostic Value of Immunotyping Combined with Targeted Therapy in Patients with Non-Small-Cell Lung Cancer and Establishment of Nomogram Model

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