National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21372068]
机构署名:
本校为其他机构
院系归属:
药学院
摘要:
A metal-free synthesis of oxindoles was achieved through the (NH<inf>4</inf>)<inf>2</inf>S<inf>2</inf>O<inf>8</inf>-mediated halocarbocyclization of alkenes. This protocol provides a practical and environmentally benign method for the construction of halo-containing oxindoles in water. The advantages of this reaction are its good functional group tolerance and mild reaction conditions. On the basis of experimental observations, a plausible reaction ...