Amoxicillin-induced aseptic meningitis: clinical features, diagnosis and management

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成果类型：

期刊论文

作者：

Fan, Zhiqiang;He, Yang;Sun, Wei;Li, Zuojun;Ye, Chao;...

通讯作者：

Wang, CJ;Ye, C

作者机构：

[Fan, Zhiqiang; He, Yang] Hunan Univ Chinese Med, Hosp 1, Dept Pharm, Changsha 410007, Hunan, Peoples R China.

[Wang, Chunjiang; Fan, Zhiqiang; Wang, CJ; He, Yang] Changsha Med Univ, Coll Pharm, Changsha 410219, Hunan, Peoples R China.

[Wang, Chunjiang; Sun, Wei; Li, Zuojun; Wang, CJ] Cent South Univ, Xiangya Hosp 3, Dept Pharm, 138 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China.

[Ye, Chao; Ye, C] Third Hosp Changsha, Dept Pharm, Changsha 410015, Hunan, Peoples R China.

通讯机构：

[Wang, CJ ] C

[Ye, C ] T

Changsha Med Univ, Coll Pharm, Changsha 410219, Hunan, Peoples R China.

Cent South Univ, Xiangya Hosp 3, Dept Pharm, 138 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China.

Third Hosp Changsha, Dept Pharm, Changsha 410015, Hunan, Peoples R China.

语种：

英文

关键词：

Aseptic meningitis;Drug-induced aseptic meningitis;Amoxicillin;Amoxicillin-clavulanate;Pharmacovigilance

期刊：

European Journal of Medical Research

ISSN：

2047-783X

年：

2023

卷：

期：

页码：

301

DOI：

10.1186/s40001-023-01251-y

基金类别：

This study was supported by Natural Science Foundation of Hunan Province (2023JJ40499), Scientific Research Fund Project of Hunan University of Chinese Medicine (2022XYLH004).

机构署名：

本校为第一机构

院系归属：

第一中医临床学院

药学院

摘要：

OBJECTIVES: The clinical features of aseptic meningitis associated with amoxicillin are unknown. The main objective of this study was to investigate the clinical characteristics of amoxicillin-induced aseptic meningitis (AIAM) and provide a reference for clinical diagnosis and treatment. METHODS: AIAM-related studies were collected by searching the relevant databases from inception to October 31, 2022. RESULTS: AIAM usually occurred 3h to 7days after amoxicillin administration in 13 males and 9 females. Twenty-one patients (95.5%) had recurrent AIAM with a total of 62 episodes. Fever (19 cases...

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Amoxicillin-induced aseptic meningitis: clinical features, diagnosis and management

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