期刊论文

He, Y.

中文

中国中西医结合杂志

1003-5370

1998

18

12

737-740

10.3321/j.issn:1003-5370.1998.12.011

国家自然科学基金资助项目!（No .392 70 84）；

本校为第一机构

目的 :观察甘露消毒丹全方、残方及加味方对柯萨奇病毒的体外抑制作用。方法 :采用组织培养技术 ,在培养细胞中观察甘露消毒丹全方、残方及加味方水煎液分别对培养细胞的最高无毒浓度 ,对柯萨奇病毒增殖产量的影响以及在不同时间内抑毒效果。结果 :甘露消毒丹全方、残方及加味方对细胞的最高无毒浓度均为 1∶40 （即 2 5 g/L） ,该浓度对柯萨奇病毒B2 、B3、B4株在培养细胞内的增殖有明显的抑制作用 ,抑制指数均 >2 ;全方对柯萨奇病毒B2 、B3、B4株在培养细胞中的增殖产量明显低于对照组 （P

OBJECTIVE: To observe the Coxackie virus inhibitory effect of Ganlu Xiaodu Dan (GLXDD), including complete recipe, incomplete recipe and supplemented recipe of it. METHODS: Using tissue culture technique, the maximal non-toxic concentration of drug on cultured cells, the influence of drug on proliferation of virus in cultured cells and the virus inhibitory effect in different time of action were observed. RESULTS: The maximal non-toxic concentration of GLXDD was 1:40 (25 g/L), no matter whether the recipe was complete, incomplete or supplementary. CLXDD in that concentration could inhibit sign...