Potential lipolytic regulators derived from natural products as effective approaches to treat obesity

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成果类型：

期刊论文

作者：

Yang, Xi-Ding;Ge, Xing-Cheng;Jiang, Si-Yi;Yang, Yong-Yu

作者机构：

[Yang, Xi-Ding; Yang, Yong-Yu] Cent South Univ, Xiangya Hosp 2, Dept Pharm, Changsha, Peoples R China.

[Yang, Xi-Ding] Cent South Univ, Xiangya Hosp 2, Phase Clin Trial Ctr 1, Changsha, Peoples R China.

[Ge, Xing-Cheng] Hunan Univ Chinese Med, Xiangxing Coll, Changsha, Peoples R China.

[Jiang, Si-Yi] Yueyang Vocat Tech Coll, Med Coll, Dept Pharm, Yueyang, Peoples R China.

[Yang, Yong-Yu] Cent South Univ, Xiangya Hosp 2, Hunan Prov Engn Res Cent Translat Med & Innovat Dr, Changsha, Peoples R China.

语种：

英文

关键词：

adipose tissue 1;Insulin resistance 2;lipolysis 3;natural product 4;obesity 5

期刊：

Frontiers in Endocrinology

ISSN：

1664-2392

年：

2022

卷：

页码：

1000739

DOI：

10.3389/fendo.2022.1000739

基金类别：

This study was supported by the National Natural Science Foundation (No. 81603171) and the Natural Science Foundation of Hunan Province (2022JJ30860 and 2022JJ30862).

机构署名：

本校为其他机构

院系归属：

湘杏学院

摘要：

Epidemic obesity is contributing to increases in the prevalence of obesity-related metabolic diseases and has, therefore, become an important public health problem. Adipose tissue is a vital energy storage organ that regulates whole-body energy metabolism. Triglyceride degradation in adipocytes is called lipolysis. It is closely tied to obesity and the metabolic disorders associated with it. Various natural products such as flavonoids, alkaloids, and terpenoids regulate lipolysis and can promote weight loss or improve obesity-related metabolic conditions. It is important to identify the specif...

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Potential lipolytic regulators derived from natural products as effective approaches to treat obesity

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