期刊论文

Effects of Danggui Buxue Decoction on TXB2 and 6-keto-PGF1α in the Model Rats with the Symptom of Qi Deficiency and Blood Stasis

中文

风湿病与关节炎

2095-4174

2014

8

29-31,34

10.3969/j.issn.2095-4174.2014.08.008

河南省2011年科技发展计划项目（112102310008）； 河南省公益类科研院所科研计划项目；

本校为第一机构

目的：探讨当归补血汤对气虚血瘀证模型大鼠TXB2及6-keto-PGF1α的影响。方法：选取清洁级SD大鼠60只,随机分为正常对照组、模型对照组和当归补血汤组,每组20只。在成功建立大鼠气滞血瘀证模型后,当归补血汤组给予当归补血汤灌胃,其余两组给予同剂量生理盐水灌胃,观察3组灌胃后第3天、第7天大鼠TXB2及6-keto-PGF1α含量并进行比较。结果：与正常对照组比较,模型对照组与当归补血汤组在第3天、第7天TXB2含量升高,6-keto-PGF1α含量下降,TXB2与6-keto-PGF1α比值升高,差异有统计学意义（P〈0.01）。与模型对照组比较,当归补血汤组第3天、第7天TXB2含量下降,6-keto-PGF1α含量上升,TXB2与6-keto-PG...

Objective：To investigate the effects of Danggui Buxue Decoction on TXB2 and 6-ke- to-PGF1α in the model rats with the symptom ofqi deficiency and blood stasis.Methods：60 SD rats of clean grade were randomly and equally divided into a normal control group,a model control group and a Danggui Buxue Decoction group.After the establishment of the model rats with the symptom of qi deficiency and blood stasis,the Danggui Buxue Decoction group were given intragastric administration with Danggui Buxue Decoction and the other two groups were given int...