Transcriptomic Profiling of Electroacupuncture Regulating the Molecular Network in Hippocampus of Rats with Cerebral Ischemia-Reperfusion Injury

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成果类型：

期刊论文

作者：

Pan, Jiang;Hong-Wei, Shen;Kai-Lin, Yang;Chen, Cheng;Shi, Wen-Ying;...

作者机构：

[Zhang, Wei; Chen, Cheng; Pan, Jiang; Lou, Bi-Dan; Shi, Wen-Ying; Ge, Jin-Wen] Hunan Univ Chinese Med, Dept Acupuncture, Affiliated Hosp 1, Changsha City, Hunan, Peoples R China.

[Kai-Lin, Yang; Pan, Jiang; Ge, Jin-Wen] Hunan Univ Chinese Med, Changsha, Hunan, Peoples R China.

[Hong-Wei, Shen] Cent South Univ, Xiangya Hosp 2, Dept Med Expt Res Ctr, Changsha City, Hunan, Peoples R China.

[Li, Sai-Qun] Changsha Cent Hosp, Dept Acupuncture, Changsha City, Hunan, Peoples R China.

语种：

英文

期刊：

Evidence-Based Complementary and Alternative Medicine

ISSN：

1741-427X

年：

2022

卷：

2022

页码：

6053106

DOI：

10.1155/2022/6053106

基金类别：

General projects of National Natural Science Foundation of China [82105002, 81273861, 81473754]; Youth program of Hunan Natural Science Foundation [2018JJ3401]

机构署名：

本校为第一机构

院系归属：

第一中医临床学院

摘要：

Objective. To explore the mechanism of electroacupuncture stimulation of the hand-taiyin meridian in regulating the molecular network of rats with cerebral ischemia-reperfusion injury based on transcriptomics. Methods. Male SD rats were randomly divided into sham operation group, model group, and electroacupuncture (EA) group. Middle cerebral artery embolization/reperfusion injury (MCAO/R) was used to establish the model group and EA group. The sham operation group only performed sham operation without modeling and any intervention, and the model group was bound daily. The EA group received el...

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Transcriptomic Profiling of Electroacupuncture Regulating the Molecular Network in Hippocampus of Rats with Cerebral Ischemia-Reperfusion Injury

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