期刊论文

Observation on changes of resting-state functional MRI in early blind adolescents based on degree centrality and seed-based functional connectivity

Liu, X.

中文

中国医学影像技术

1003-3289

2021

37

01

26-29

10.13929/j.issn.1003-3289.2021.01.005

本校为第一机构

目的基于体素度中心度(DC),结合种子点功能连接(SFC)方法,以静息态功能MRI(rs-fMRI)观察早盲青少年静息态下脑功能连接异常改变。方法对16例早盲青少年(观察组)和性别及年龄相匹配的16名正常视力志愿者(对照组)采集rs-fMRI数据,比较2组DC值差异;以组间DC值存在显著差异的脑区作为ROI,采用SFC方法计算其与其他脑区间的功能连接。结果观察组初级视觉皮层(右侧距状沟、双侧舌回)DC值较对照组降低,而语言皮层(双侧三角部额下回、右侧岛叶)DC值较对照组升高(P均

Objective: To observe the abnormal changes of brain functional connectivity in early blind adolescents using resting-state functional MRI (rs-fMRI) based on degree centrality (DC) and seed-based functional connectivity (SFC) methods by. Methods: Totally 16 early blind adolescents (observation group) and 16 age- and gender-matched sighted volunteers (control group) were recruited. rs-fMRI data were collected, and DC values were compared between groups. Taken brain regions with significant differences of DC values between groups as ROI, their fun...