期刊论文

Liu, X.

中文

中国医学影像技术

1003-3289

2022

38

5

653-657

10.13929/j.issn.1003-3289.2022.05.003

本校为第一机构

目的基于颅脑MRI,评价以基于体素的形态测量学(VBM)及基于表面积的形态测量学(SBM)方法观察早盲青少年(EBA)脑皮层形态学改变的可行性。方法选取23例EBA(EBA组)及21名视力正常的青少年志愿者(对照组),采集2组颅脑高分辨率3D-T1WI。以VBM方法分析2组间皮层体积(CV)差异有统计学意义的脑区;采用SBM方法测量皮层厚度(CT)、CV及表面积(SA),比较组间各结构指标的差异。结果VBM结果显示,EBA组右侧距状沟及左侧额中回CV较对照组显著减小(P均

Objective: To explore the feasibility of voxel-based morphological (VBM) and surface-based morphometry (SBM) analysis for observation on brain cortical morphology changes in early blind adolescents (EBA) based on cranial MRI. Methods: Twenty-three EBA (EBA group) and 21 adolescents with normal vision (control group) were enrolled, and high-resolution 3D-T1WI were acquired. VBM method was used to analyze the brain regions with significant differences of cortical volume (CV) between groups, while SBM method was used to measure cortical thickness ...