Three new indolyl diketopiperazine metabolites from the antarctic soil-derived fungus Penicillium sp SCSIO 05705

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成果类型：

期刊论文

作者：

Wang, Junfeng;He, Weijun;Qin, Xiaochu;Wei, Xiaoyi;Tian, Xinpeng;...

通讯作者：

Liu, Yonghong

作者机构：

[Wang, Fazuo; He, Weijun; Wang, Junfeng; Tian, Xinpeng; Liu, Yonghong; Liao, Shengrong; Yang, Bin] Chinese Acad Sci, CAS Key Lab Trop Marine Bioresources & Ecol, Guangdong Key Lab Marine Mat Med, RNAM Ctr Marine Microbiol,South China Sea Inst Oc, Guangzhou 510301, Guangdong, Peoples R China.

[He, Weijun; Zhou, Xiaojiang] Hunan Univ Chinese Med, Coll Pharm, Changsha 410208, Hunan, Peoples R China.

[Qin, Xiaochu; Tu, Zhengchao] Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, Guangzhou 510530, Guangdong, Peoples R China.

[Wei, Xiaoyi] Chinese Acad Sci, Key Lab Plant Resources Conservat & Sustainable U, South China Bot Garden, Guangzhou 510650, Guangdong, Peoples R China.

[Liao, Li; Chen, Bo] Polar Res Inst China, SOA Key Lab Polar Sci, Shanghai 200136, Peoples R China.

通讯机构：

[Liu, Yonghong] C

Chinese Acad Sci, CAS Key Lab Trop Marine Bioresources & Ecol, Guangdong Key Lab Marine Mat Med, RNAM Ctr Marine Microbiol,South China Sea Inst Oc, Guangzhou 510301, Guangdong, Peoples R China.

语种：

英文

期刊：

RSC Advances

ISSN：

2046-2069

年：

2015

卷：

期：

页码：

68736-68742

DOI：

10.1039/c5ra10828d

基金类别：

National Key Basic Research Program of China (973)'s ProjectNational Basic Research Program of China [2011CB915503]; Open Foundation of the SOA key Laboratory for Polar Science; Polar Research Institute of China [KP201305]; National High Technology Research and Development Program (863 Program)National High Technology Research and Development Program of China [2012AA092104]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31270402, 21172230, 41476135, 41476136]; Strategic Priority Research Program of the Chinese Academy of SciencesChinese Academy of Sciences [XDA11030403]; Guangdong Marine Economic Development and Innovation of Regional Demonstration Project [GD2012-D01-001]

机构署名：

本校为其他机构

院系归属：

药学院

摘要：

Three new indolyl diketopiperazine derivatives, penillines A and B (1 and 3), isopenilline A (2), together with seven known alkaloid compounds (E)-3-(1H-imidazole-4-yimethylene)-6-(1H-indl-3-ylmethyl)-2,5-piperazinediol (4), penilloid A (5), meleagrin (6), neoxaline (7), questiomycin A (8), N-(2-hydroxyphenyl)-acetamide (9), 2-benzoxazolinone (10), were isolated from the Antarctic soil-derived fungus Penicillium sp. SCSIO 05705. The new structures of 1-3 were elucidated on the basis of 1D and 2D NMR, mass spectra, CD spectra, and quantum chemical calculations. All the isolated compounds were t...

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Three new indolyl diketopiperazine metabolites from the antarctic soil-derived fungus Penicillium sp SCSIO 05705

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