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Puerarin ameliorates cognitive deficits in streptozotocin-induced diabetic rats

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成果类型:
期刊论文
作者:
Liu, Xianchu;Mo, Yanzhi;Gong, Jingbo;Li, Zhuang;Peng, Huan;...
通讯作者:
Xie, Jingtao
作者机构:
[Ke, Zhaowen; Mo, Yanzhi; Chen, Jiaxue; Gong, Jingbo; Liu, Xianchu; Li, Zhuang; Wang, Qichao; Xie, Jingtao; Peng, Huan] Hunan Univ Chinese Med, Dept Appl Psychol, Changsha, Hunan, Peoples R China.
通讯机构:
[Xie, Jingtao] H
Hunan Univ Chinese Med, Dept Appl Psychol, Changsha, Hunan, Peoples R China.
语种:
英文
关键词:
Bcl-2;Cognitive;DACD;Inflammation;Oxidative stress;Puerarin
期刊:
Metabolic Brain Disease
ISSN:
0885-7490
年:
2016
卷:
31
期:
2
页码:
417-423
基金类别:
Hunan Provincial Education DepartmentHunan Provincial Education Department [60010511]; Science and Technology Foundation of Changsha City [K1403011-31]
机构署名:
本校为第一且通讯机构
院系归属:
人文与管理学院
摘要:
Previous research has indicated that Diabetes is a high risk of learning and memory deficits. Puerarin, an isoflavonoid extracted from Kudzu roots, has been reported to possess antioxidant, anti-inflammatory, anti-apoptotic and anti-diabetic properties which are useful in the treatment of various diseases. Recently, Puerarin was found to have the effects on learning and memory performances in humans and animal models. However, up to now, there is no detailed evidence on the effect of Puerarin on diabetes-associated cognitive decline (DACD). In ...

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