期刊论文

中文

中国中医药信息杂志

1005-5304

2012

19

11

41-43

10.3969/j.issn.1005-5304.2012.11.016

国家自然科学基金（30973856） 湖南省中医药科研计划（201142） 湖南省研究生科研创新项目（CX2011B335）

本校为第一机构

目的观察益气解毒方提取物对鼻咽癌CNE2细胞及移植瘤的抑制作用。方法采用MTT法测定益气解毒方多糖提取物、乙酸乙酯提取物(EAE)、乙醇提取物对CNE2细胞体外增殖的影响。建立CNE2裸鼠移植瘤模型,随机分为模型组、EAE组、顺铂(DDP)组和联合治疗组,分别给予生理盐水、益气解毒方EAE、DDP注射液以及EAE联合DDP注射液,12 d后检测各治疗组的肿瘤抑制率。结果益气解毒方EAE对CNE2细胞具有明显的抑制作用,并呈明显的剂量效应关系(P

Objective To observe the inhibition effect of extracted parts from Qi-Boosting Toxin-Resolving Formula on nasopharyngeal carcinoma CNE2 cell and transplanted tumor.Methods MTT method was used to determine the effect of polysaccharide extract,ethyl acetate extract（EAE） and ethanol extract on CNE2 cell proliferation in vitro.CNE2 nude mice transplant tumor model was established and randomly divided into model group,EAE group,DDP group and the combined treatment group（n=8）,and was given saline,Qi-Boosting Toxin-Resolving Formula EAE,DDP inject...