期刊论文

中文

中华中医药学刊

1673-7717

2008

26

8

1682-1683

10.13193/j.archtcm.2008.08.83.chenqh.068

教育部博士点基金资助项目（20050541005） 湖南省自然科学基金资助项目（02JJY4014） 湖南省教育厅重点项目（04A039）

本校为第一机构

目的:观察经丹参酮ⅡA干预后的心血瘀阻证大鼠在心电图和心肌HBFP染色上的变化。方法:用垂体后叶素尾静脉注射法复制心血瘀阻证大鼠模型。将W istar大鼠随机分为3组:丹参酮ⅡA组、心血瘀证模型组、正常对照组。各组均在灌胃10天后造模,测量大鼠各时间点的心电图后,取心脏做HBFP特殊染色。结果:丹参酮ⅡA组与心血瘀阻证模型组比较可以显著对抗由垂体后叶素诱发的心血瘀阻证心电图J点变化（P

Objective ：To research the effect of heart blood stasis rat intervened by Tanshinone IIA on the electrocardiogram and expression by special pathologic dying method （HBFP）. Methods：Randomly divided Wistar rat into 3 groups, they are Tanshinone IIA group, heart blood stasis group, and normal group. The model of heart blood stasis （myocardial isehemia） was established with Pit inject via caudal vein. Every rat was examined ECG after they were in narcosis. After injection record every rat ECG ,then get the cardiac muscle to examine the expres...