期刊论文

Intervention of Acupuncture at Stomach Meridian Acupoints for DIO Rat Insulin Resistant and Hypothalamus IRS1 and Tyrosine Phosphorylation Expression

中文

中医药信息

1002-2406

2013

30

1

70-72

10.3969/j.issn.1002-2406.2013.01.029

12K084:湖南省高等学校创新平台开放基金 2012:湖南省大学生研究性学习和创新性实验计划

本校为第一机构

目的:观察针刺足阳明经四白、天枢、足三里、内庭等穴对高脂饮食诱导的肥胖大鼠胰岛素抵抗及下丘脑胰岛素受体后IRS1及其酪氨酸磷酸化的影响.方法:予高脂饮食诱导的30只肥胖大鼠随机分为肥胖模型组,针刺足阳明经穴组,针刺非经穴组,并以普饲喂养的10只大鼠做空白对照,连续干预4周.结果:1)针刺足阳明经穴组能显著抑制高脂模型大鼠体质量,与非经穴组比较,有显著性差异(P＜0.05).2)与空白组比较,肥胖模型组及非经穴组空腹血糖(FPG)、空腹胰岛素(FINS)、HOMA-指数( HOMA - INDEX)均显著升高(P＜0.05或P＜0.01).针刺组大鼠FPG、FINS、HOMA - INDEX均显著下降,与模型组及非经穴组比较,差异具有统计学意...

Objective： To explore the effects of acupuncture at Stomach Meridian acupoints including Sibai,Tianshu,Zusanli and Neiting on Diet Induced Obesity（DIO） rats＇ insulin resistant and hypothalamus insulin receptor substrate-1（IRS1） and tyrosine phosphorylation expression.Methods： 30 DIO rats were divided into three groups,each with 10 rats,including DIO model group（DIO group）,DIO model with acupuncture at acupoints of Stomach Meridian group（ST group）,DIO model with acupuncture at non-acupoints group（NA group）,while 10 normal rats were ...