Systematic investigations were made on synthometrics and its applications. Synthometrics was regarded as `Chemometrics in Synthetic Chemistry' or `Synthetic Chemometrics'. Uniform or homogeneous design (UD or HD) and stepwise regression (SR) were used, in this paper, for response modelling and synthesis optimization for preparation of allantion by the pathway of trichloroaldehyde (TCA). The primary factor was found to be reaction temperature through experiments. The optimal conditions for preparation of allantion...
