期刊论文

He, G.-X.

中文

中国中药杂志

1001-5302

2003

28

12

1188-1190

10.3321/j.issn:1001-5302.2003.12.027

湖南省卫生厅中医药科研项目

本校为其他机构

目的:研究二氢杨梅素(DMY)抗脂质过氧化作用.方法:采用分光光度法测定DMY对由Fe2+维生素C(Fe2+-Vit C)体系、Fe2+-过氧化氢(Fe2+-H2O2)体系、Fe-半胱氨酸(Fe2+-Cys)体系诱导的脂质过氧化的抑制作用.结果:DMY能抑制离体大鼠脑、心、肝匀浆及线粒体脂质过氧化并表现出剂量依赖关系.结论:DMY具有较好的抗脂质过氧化作用,具有进一步研究与开发价值.

Objective: To study the effects of Dihydromyricetin(DMY) on antilipid-peroxidation. Method: The antilipid-peroxidation of DMY on heart, liver, brain tissue homogenate and mitochondria was measured by the determination of malondiadehyde (MDA) induced by Fe 2+ -Vit C, Fe 2+ -H 2 O 2 ,Fe-Cys with TBA spectrometric method. Result: DMY could inhibit the lipid peroxidation of homogenate and mitochondria. The inhibition exhibited concentration-dependent manner. Conclusion: DMY has good an...