期刊论文

Li, C.

中文

中国中药杂志

1001-5302

2013

38

17

2818-2825

10.4268/cjcmm20131715

中央级公益性科研院所基本科研业务费专项资金项目（ZZ070828）； 北京市自然科学基金项目（7132152）；

本校为其他机构

对甘青乌头Aconitum tanguticum全草的化学成分进行研究。应用硅胶,ODS,Sephadex LH-20,制备HPLC等各种色谱技术进行分离纯化,采用MS,NMR等波谱技术鉴定化合物结构。甘青乌头乙醇总提取物经石油醚、乙酸乙酯萃取后的剩余水溶液经AB-8大孔吸附树脂,依次用水,30%,60%,95%乙醇洗脱,合并回收溶剂分别得到各洗脱部分。从30%,60%乙醇洗脱部分共分离得到19个化合物,分别鉴定为紫丁香苷(1),香草酸4-O-β-D-阿洛糖苷(2),阿魏酸4-O-β-D-阿洛糖苷(3),阿魏酸4-O-β-D-葡萄糖苷(4),芥子酸4-O-β-D-葡萄糖苷(5),4-羟基-肉桂醇-4-O-β-D-葡萄糖苷(6),槲皮素-3-O-α-L-鼠李糖基-(1→2)-[α-L-鼠李糖基-(1→6)]-...

Nineteen compounds were isolated from the whole plants of Aconitum tanguticum by means of various of chromatographic techniques such as silica gel, ODS, sephadex LH-20 and preparative HPLC, and their structures were elucidated as syringin (1), vanillic acid-4-O-beta-D-allopyranoside (2), (E) -ferulic acid 4-O-beta-D-allopyranoside (3), (E) -ferulic acid-4-O-beta-glucopysoside (4), (E) -sinapic acid-4-O-beta-glucopyranoside (5), (E) 4-hydroxycinnamyl alcohol 4-O-beta-D-glucopyranoside (6), quercetin 3-O-alpha-L-rhamnopyranosyl-(1 --> 2) -[alpha-L-rhamnopyranosyl-(1 --> 6)] -beta-D-galactopyrano...