The aim of this study was to explore the mechanism of icaritin-induced ferroptosis in hepatoma HepG2 cells.By bioinfor-matics screening,the target of icariin's intervention in liver cancer ferroptosis was selected,the protein-protein interaction(PPI)net-work was constructed,the related pathways were focused,the binding ability of icariin and target protein was evaluated by molecular docking,and the impact on patients'survival prognosis was predicted and the clinical prediction model was built.CCK-8,EdU,and clonal formation assays were used to d...