期刊论文

Research advance in effects of EGCG and AcEGCG on oxidative stress in cells

Li, L.

中文

中国新药杂志

1003-3734

2018

27

5

527-532

15C1037:教育厅项目 :湖南省重点学科建设项目(十二五) :湖南省***卫生人才225工程项目 :湖南省中药饮片标准化 :功能工程技术研究中心资助项目

本校为第一且通讯机构

表没食子儿茶素没食子酸酯（EGCG）是茶叶中的主要活性成分,全乙酰化表没食子儿茶素没食子酸酯（AcEGCG）是EGCG的乙酰化衍生物。本文从细胞氧化应激方面综述了2种化合物的药理作用,总结出AcEGCG在抗细胞氧化应激方面的优势,并为其新药研发和作用机制研究提供借鉴。

Epigallocatechin gallate (EGCG) is the main active ingredient in tea, and the total acetylated epigallocatechin gallate (AcEGCG) is an acetylated derivative of EGCG. To provide reference for research on the drug development and action mechanisms of AcEGCG, in this paper we reviewed the pharmacological effects of two compounds from the aspects of oxidative stress, and summarized the advantages of AcEGCG in anti-oxidative ability on cell stress. © 201...