The pulmonary administration of solid lipid nanoparticles is characterized by slow release, low toxicity, and local targeting, which has attracted increasing attention from researchers. Currently commonly used formulations for pulmonary delivery of drugs include inhalation aerosols, inhalation powder aerosols and inhalation sprays, among which the stability of solid lipid nanoparticles can be improved to a certain extent by making powder aerosol. In this paper, the characteristics, preparation methods, quality evaluation, toxicological evaluati...