Objective :To optimize the ethanol extraction process for compound anti -inflammatory patch. Methods:An orthogonal design (using L9 (34) orthogonal array) was used to investigate the effects of ethanol volume, extraction time, and soaking time on the yields of geniposide and extract. Results : In the optimal process, soaking was performed for 30 min, and extraction was carried out twice (1.5 h and 1 h) using 70% ethanol (8 times and 6 times). Conclusion:The optimized extraction process can provide a reference for the p...