期刊论文

中文

湖南中医杂志

1003-7705

2015

31

6

152-153

10.16808/j.cnki.issn1003-7705.2015.06.084

湖南省自然科学基金资助项目（编号:S2014J5041）； 湖南中医药大学中西医结合临床重点学科项目；

本校为第一机构

目的:探讨寒热证型与甲状腺激素、炎性细胞因子的关系.方法:取清洁级Wistar大鼠60只,随机取20只为正常对照组,另40只各取20只分别制备热证及寒证模型,造模成功后设为热证模型组和寒证模型组,比较3组大鼠血清甲状腺激素及炎性细胞因子水平变化情况.结果:实验后血清三碘甲状腺氨酸(T3)、四碘甲状腺氨酸(T4)、游离三碘甲腺原氨酸(FT3)、游离四碘甲腺原氨酸(FT4)、肿瘤坏死因子α(TNF-α)及白细胞介素-8(IL-8)6项指标组间比较,差异均有统计学意义(P =0.000),且热证模型组＞正常对照组＞寒证模型组.结论:寒热证模型组的血清甲状腺激素及炎性细胞因子水平不同,内分泌激素水平及炎性细胞因子水平的高低...

Objective ： To investigate the relationship of co ry cytokines. Methods：Sixty clean Wistar rats were randomly odel group, and cold syndrome model group. The changes in ld/hot syndrome with thyroid hormone and inflamma- and equally divided into control group, hot syndrome serum levels of thyroid hormone and inflammatory cy-tokines were compared between the three groups. Results ：There were significant differences in serum levels of triio- dothyronine （ T3 ）, thyroxine （ T4）, free T3, free T4, tumor necrosis factor - α, and interleukin - ...